MATRIX METALLOPROTEINASES: KEY PLAYERS IN TISSUE REMODELING AND DISEASE

Matrix metalloproteinases MMP enzymes (MMPs) are a large cohort of zinc-dependent endopeptidases. These proteases play critical functions in {extracellularcell matrix remodeling, contributing to physiological processes such as wound healing, embryogenesis, and angiogenesis. However, dysregulation in MMP activity is associated to a wide range of pat